The primary objective of treatment is to ensure a rapid and complete elimination of the Plasmodium parasite from the patient’s blood in order to prevent progression of uncomplicated malaria to severe disease or death, and to chronic infection that leads to malaria-related anaemia.

Malaria is treated with antimalarial drugs and measures to control symptoms, including medications to control fever, antiseizure medications when needed, fluids and electrolytes. The type of medications that are used to treat malaria depends on the severity of the disease and the likelihood of chloroquine resistance.